Concepedia

Single-cell Epigenomics

Single-Cell Epigenomics is a subfield of epigenomics and single-cell biology that investigates genome-wide epigenetic states—such as DNA methylation, histone modifications, chromatin accessibility, and higher-order chromatin structure—at single-cell resolution, primarily using sequencing-based assays, to characterize cell-to-cell epigenetic heterogeneity and its consequences for gene regulation, cell identity, and function.

572

Publications

71.6K

Citations

4.7K

Authors

1K

Institutions

Publications per year

2017–2026

498

Parents

Children

Publications

572

Single-cell chromatin accessibility reveals principles of regulatory variation

Jason D. Buenrostro, Beijing Wu, Ulrike Litzenburger et al. · Nature · 2015 · 2.5K citations · Full text

, , +13

CUT&Tag for efficient epigenomic profiling of small samples and single cells

Hatice S Kaya-Okur, Steven J. Wu, Christine A. Codomo et al. · Nature Communications · 2019 · 2.2K citations · Full text

, , +15

chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data

Alicia N. Schep, Beijing Wu, Jason D. Buenrostro et al. · Nature Methods · 2017 · 1.9K citations · Full text

, , +14

Single-cell chromatin state analysis with Signac

Tim Stuart, Avi Srivastava, Shaista Madad et al. · Nature Methods · 2021 · 1.8K citations · Full text

, , +12

ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis

Jeffrey M. Granja, M. Ryan Corces, Sarah E. Pierce et al. · Nature Genetics · 2021 · 1.5K citations · Full text

, , +17

1–5 of 572

Authors

4.7K

  1. WJ
    William J. Greenleaf

    Stanford University, United States

    28 publications · 10.9K citations

    21

    h-index

  2. BR
    Bing Ren

    University of California San Diego, United States

    22 publications · 3.9K citations

    21

    h-index

  3. JR
    Joseph R. Ecker

    Salk Institute for Biological Studies, United States

    23 publications · 3.6K citations

    20

    h-index

  4. MM
    M. Margarita Behrens

    University of California San Diego, United States

    22 publications · 3.9K citations

    20

    h-index

  5. JR
    Joseph R. Nery

    Salk Institute for Biological Studies, United States

    20 publications · 3.4K citations

    18

    h-index

1–5 of 4.7K

Institutions

1K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    59 h-index

    165 publications

    48.1K citations

  2. Harvard University

    Cambridge, United States

    39 h-index

    335 publications

    62.4K citations

  3. Stanford University

    Stanford, United States

    39 h-index

    407 publications

    109.3K citations

  4. University of California San Diego

    San Diego, United States

    36 h-index

    321 publications

    71.2K citations

  5. Broad Institute

    Cambridge, United States

    34 h-index

    249 publications

    62.6K citations

  6. University of Washington

    Seattle, United States

    26 h-index

    147 publications

    57.8K citations

  7. Chan Zuckerberg Initiative (United States)

    Redwood City, United States

    23 h-index

    69 publications

    15.1K citations

  8. Peking University

    Beijing, China

    23 h-index

    216 publications

    30.6K citations

1–8 of 1K

Venues

  1. Nature Communications

    50 publications · 8.9K citations

    38

    h-index

  2. Nature Biotechnology

    26 publications · 7.1K citations

    26

    h-index

  3. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 76 publications · 2.1K citations

    25

    h-index

  4. Nature Methods

    22 publications · 8.5K citations

    21

    h-index

  5. Genome biology

    21 publications · 2.7K citations

    19

    h-index

1–5