Eric S. Dawson

Discovery, Synthesis, And Structure-Based Optimization of a Series of <i>N</i>-(<i>tert</i>-Butyl)-2-(<i>N</i>-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease

Jon Jacobs, Valerie Grum‐Tokars, Ya Zhou et al. · Journal of Medicinal Chemistry · 2012 · 208 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding

Mark Turlington, Aspen Chun, Sakshi Tomar et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 132 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Discovery and Characterization of Novel Subtype-Selective Allosteric Agonists for the Investigation of M₁ Receptor Function in the Central Nervous System

Evan P. Lebois, Thomas M. Bridges, L. Michelle Lewis et al. · ACS Chemical Neuroscience · 2009 · 100 citations

Medicine, Neuroscience, Pharmacology +17

The Discovery and Characterization of ML218: A Novel, Centrally Active T-Type Calcium Channel Inhibitor with Robust Effects in STN Neurons and in a Rodent Model of Parkinson’s Disease

Zixiu Xiang, Analisa D. Thompson, John T. Brogan et al. · ACS Chemical Neuroscience · 2011 · 99 citations · Full text

Pharmacy, Neuroscience, Pharmacology +17

Selective Inhibition of the K_ir2 Family of Inward Rectifier Potassium Channels by a Small Molecule Probe: The Discovery, SAR, and Pharmacological Characterization of ML133

Hao‐ran Wang, Meng Wu, Haibo Yu et al. · ACS Chemical Biology · 2011 · 99 citations

Medicine, Medicinal Chemistry, Pharmacology +17