Aspen Chun

Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding

Mark Turlington, Aspen Chun, Sakshi Tomar et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 132 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Investigating Metabotropic Glutamate Receptor 5 Allosteric Modulator Cooperativity, Affinity, and Agonism: Enriching Structure-Function Studies and Structure-Activity Relationships

Karen J. Gregory, Meredith J. Noetzel, Jerri M. Rook et al. · Molecular Pharmacology · 2012 · 92 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Exploration of Allosteric Agonism Structure–Activity Relationships within an Acetylene Series of Metabotropic Glutamate Receptor 5 (mGlu₅) Positive Allosteric Modulators (PAMs): Discovery of 5-((3-Fluorophenyl)ethynyl)-<i>N</i>-(3-methyloxetan-3-yl)picolinamide (ML254)

Mark Turlington, Meredith J. Noetzel, Aspen Chun et al. · Journal of Medicinal Chemistry · 2013 · 28 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Discovery of VU2957 (Valiglurax): An mGlu₄ Positive Allosteric Modulator Evaluated as a Preclinical Candidate for the Treatment of Parkinson’s Disease

Joseph D. Panarese, Darren W. Engers, Yong‐Jin Wu et al. · ACS Medicinal Chemistry Letters · 2018 · 25 citations · Full text

Pharmacy, Pharmacology, Toxicology +14

Preparation of H,4 PyrrolidineQuin-BAM (PBAM)

Tyler A. Davis, Mark C. Dobish, Kenneth E. Schwieter et al. · Organic Syntheses · 2012 · 20 citations · Full text

Natural Sciences, Chemistry, Organic Chemistry +1