Concepedia

Author

Jerri M. Rook

Vanderbilt University

Also Known As

J M Rook, J Rook, Jerri M Rook, Jerri M. Rook, Jerri Rook, Jerri. M. Rook, Jerri M. Rook, Rook, J.M., Rook, Jerri M.

77

Publications

2.3K

Citations

28

H-Index

68

Concepts

All Affiliations

Vanderbilt UniversityVanderbilt University Medical CenterMonash UniversityJohn F. Kennedy Center for the Performing ArtsUniversity of Kansas Medical Center
JM

About

Jerri M. Rook is an author at Vanderbilt University specializing in medicine, neuroscience, and neuropharmacology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

16

18

977

2

Social Sciences

11

11

598

3

Health Sciences

2

2

95

4

Natural Sciences

1

1

28

5

Anesthesia

1

1

48

Jerri M. Rook

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42

Publications

2.1K

Citations

28

H-Index

YearCitations

Discovery of Novel Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 Reveals Chemical and Functional Diversity and In Vivo Activity in Rat Behavioral Models of Anxiolytic and Antipsychotic Activity

Alice L. Rodriguez, Mark D. Grier, Carrie K. Jones,

Molecular Pharmacology

2010

177

Biased mGlu 5 -Positive Allosteric Modulators Provide In Vivo Efficacy without Potentiating mGlu 5 Modulation of NMDAR Currents

Jerri M. Rook, Zixiu Xiang, Xiaohui Lv,

Neuron

2015

128

Functional Impact of Allosteric Agonist Activity of Selective Positive Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 in Regulating Central Nervous System Function

Meredith J. Noetzel, Jerri M. Rook, Paige N. Vinson,

Molecular Pharmacology

2011

127

Unique Signaling Profiles of Positive Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 Determine Differences in In Vivo Activity

Jerri M. Rook, Meredith J. Noetzel, Wendy A. Pouliot,

Biological Psychiatry

2012

106

Potentiation of M1 Muscarinic Receptor Reverses Plasticity Deficits and Negative and Cognitive Symptoms in a Schizophrenia Mouse Model

Ayan Ghoshal, Jerri M. Rook, Jonathan W. Dickerson,

Neuropsychopharmacology

2015

102

Metabotropic glutamate receptor 3 activation is required for long-term depression in medial prefrontal cortex and fear extinction

Adam G. Walker, Cody J. Wenthur, Zixiu Xiang,

Proceedings of the National Academy of Sciences

2015

96

Investigating Metabotropic Glutamate Receptor 5 Allosteric Modulator Cooperativity, Affinity, and Agonism: Enriching Structure-Function Studies and Structure-Activity Relationships

Karen J. Gregory, Meredith J. Noetzel, Jerri M. Rook,

Molecular Pharmacology

2012

92

M1-positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognition

Sean P. Moran, Jonathan W. Dickerson, Hyekyung P. Cho,

Neuropsychopharmacology

2018

79

Discovery of Molecular Switches That Modulate Modes of Metabotropic Glutamate Receptor Subtype 5 (mGlu<sub>5</sub>) Pharmacology in Vitro and in Vivo within a Series of Functionalized, Regioisomeric 2- and 5-(Phenylethynyl)pyrimidines

Sameer Sharma, Jeffrey Kedrowski, Jerri M. Rook,

Journal of Medicinal Chemistry

2009

73

Morphine-induced early delays in wound closure: Involvement of sensory neuropeptides and modification of neurokinin receptor expression

Jerri M. Rook, Wohaib Hasan, Kenneth E. McCarson

Biochemical Pharmacology

2009

66

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