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Functional Impact of Allosteric Agonist Activity of Selective Positive Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 in Regulating Central Nervous System Function

Meredith J. Noetzel, Jerri M. Rook, Paige N. Vinson, Hyekyung P. Cho, Emily Days, Ying Zhou, Alice L. Rodriguez, Hilde Lavreysen, Shaun R. Stauffer, Colleen M. Niswender,

Molecular Pharmacology · 2011 · 127 citations · 32 references

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32

Subanesthetic Effects of the Noncompetitive NMDA Antagonist, Ketamine, in Humans

John H. Krystal · Archives of General Psychiatry · 1994 · 3.3K citations

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Altered synaptic plasticity in a mouse model of fragile X mental retardation

Kimberly M. Huber, Sean Gallagher, Stephen T. Warren et al. · Proceedings of the National Academy of Sciences · 2002 · 1.3K citations

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Mice Lacking Metabotropic Glutamate Receptor 5 Show Impaired Learning and Reduced CA1 Long-Term Potentiation (LTP) But Normal CA3 LTP

Youming Lu, Zhengping Jia, Christopher Janus et al. · Journal of Neuroscience · 1997 · 630 citations · Full text

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Metabotropic Glutamate Receptors 1 and 5 Differentially Regulate CA1 Pyramidal Cell Function

Guido Mannaioni, Michael J. Marino, Ornella Valenti et al. · Journal of Neuroscience · 2001 · 441 citations · Full text

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Activation of Metabotropic Glutamate Receptor 5 Has Direct Excitatory Effects and Potentiates NMDA Receptor Currents in Neurons of the Subthalamic Nucleus

Hazar Awad, George W. Hubert, Yoland Smith et al. · Journal of Neuroscience · 2000 · 420 citations · Full text

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