Hilde Lavreysen

JNJ16259685, a highly potent, selective and systemically active mGlu1 receptor antagonist

Hilde Lavreysen, Ria Wouters, François Bischoff et al. · Neuropharmacology · 2004 · 138 citations

Molecular Physiology, Biochemistry, G Protein-coupled Receptor +9

Biased mGlu 5 -Positive Allosteric Modulators Provide In Vivo Efficacy without Potentiating mGlu 5 Modulation of NMDAR Currents

Jerri M. Rook, Zixiu Xiang, Xiaohui Lv et al. · Neuron · 2015 · 128 citations · Full text

Signal Transduction, Molecular Physiology, Mglu 5 +9

Functional Impact of Allosteric Agonist Activity of Selective Positive Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 in Regulating Central Nervous System Function

Meredith J. Noetzel, Jerri M. Rook, Paige N. Vinson et al. · Molecular Pharmacology · 2011 · 127 citations · Full text

[3H]R214127: A Novel High-Affinity Radioligand for the mGlu1 Receptor Reveals a Common Binding Site Shared by Multiple Allosteric Antagonists

Hilde Lavreysen, Cor Janssen, François Bischoff et al. · Molecular Pharmacology · 2003 · 115 citations · Full text

Effects of mGlu1 receptor blockade on anxiety-related behaviour in the rat lick suppression test

Thomas Steckler, Hilde Lavreysen, Ana M.M. Oliveira et al. · Psychopharmacology · 2004 · 90 citations

Stress Hormone, Psychiatry, Behavioral Neuroscience +13