Valerie Grum‐Tokars

Evaluating the 3C-like protease activity of SARS-Coronavirus: Recommendations for standardized assays for drug discovery

Valerie Grum‐Tokars, Kiira Ratia, Adrian Begaye et al. · Virus Research · 2007 · 216 citations

Life Sciences, Infectious Diseases, Molecular Biology +15

Discovery, Synthesis, And Structure-Based Optimization of a Series of <i>N</i>-(<i>tert</i>-Butyl)-2-(<i>N</i>-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease

Jon Jacobs, Valerie Grum‐Tokars, Ya Zhou et al. · Journal of Medicinal Chemistry · 2012 · 208 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Mutations in Capillary Morphogenesis Gene-2 Result in the Allelic Disorders Juvenile Hyaline Fibromatosis and Infantile Systemic Hyalinosis

Oonagh Dowling, Analisa DiFeo, Maria Celeste M. Ramirez et al. · The American Journal of Human Genetics · 2003 · 196 citations · Full text

Medicine, Genetics, Molecular Genetics +10

Structure-Based Design of Novel HIV-1 Protease Inhibitors To Combat Drug Resistance

Arun K. Ghosh, P. Sridhar, Sofiya Leshchenko et al. · Journal of Medicinal Chemistry · 2006 · 155 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors

Arun K. Ghosh, Gangli Gong, Valerie Grum‐Tokars et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 137 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12