Concepedia

Author

Sofiya Leshchenko

University of Illinois Chicago

Also Known As

Sofiya Leshchenko

9

Publications

958

Citations

7

H-Index

6

Concepts

All Affiliations

University of Illinois ChicagoGeorgia State UniversityPurdue University West LafayetteKumamoto UniversityRosalind Franklin University of Medicine and Science
SL

About

Sofiya Leshchenko is an author at University of Illinois Chicago specializing in structural biology, hiv, and natural sciences.

Top Concepts

#ConceptH-IndexPublicationsCitations

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Medicine

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Natural Sciences

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Biochemistry

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Molecular Biology

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Structural Biology

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Sofiya Leshchenko

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7

Publications

958

Citations

7

H-Index

YearCitations

High Resolution Crystal Structures of HIV-1 Protease with a Potent Non-peptide Inhibitor (UIC-94017) Active Against Multi-drug-resistant Clinical Strains

Yunfeng Tie, Péter Boross, Yuan‐Fang Wang,

Journal of Molecular Biology

2004

217

Structure-Based Design of Novel HIV-1 Protease Inhibitors To Combat Drug Resistance

Arun K. Ghosh, P. Sridhar, Sofiya Leshchenko,

Journal of Medicinal Chemistry

2006

155

Ultra-high Resolution Crystal Structure of HIV-1 Protease Mutant Reveals Two Binding Sites for Clinical Inhibitor TMC114

Andrey Kovalevsky, Fengling Liu, Sofiya Leshchenko,

Journal of Molecular Biology

2006

143

Effectiveness of Nonpeptide Clinical Inhibitor TMC-114 on HIV-1 Protease with Highly Drug Resistant Mutations D30N, I50V, and L90M

Andrey Kovalevsky, Yunfeng Tie, Fengling Liu,

Journal of Medicinal Chemistry

2006

142

Stereoselective Photochemical 1,3-Dioxolane Addition to <i>5-</i>Alkoxymethyl-2(5<i>H</i>)-furanone:  Synthesis of Bis-tetrahydrofuranyl Ligand for HIV Protease Inhibitor UIC-94017 (TMC-114)

Arun K. Ghosh, Sofiya Leshchenko, Marcus W. Noetzel

The Journal of Organic Chemistry

2004

134

Design and synthesis of novel HIV-1 protease inhibitors incorporating oxyindoles as the <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si1.gif" overflow="scroll"><mml:mrow><mml:msubsup><mml:mrow><mml:mi mathvariant="normal">P</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow><mml:mrow><mml:mo>′</mml:mo></mml:mrow></mml:msubsup></mml:mrow></mml:math>-ligands

Arun K. Ghosh, Gary E. Schiltz, P. Sridhar,

Bioorganic & Medicinal Chemistry Letters

2006

106

Structure-Based Design:  Synthesis and Biological Evaluation of a Series of Novel Cycloamide-Derived HIV-1 Protease Inhibitors

Arun K. Ghosh, Lisa Swanson, Hanna Cho,

Journal of Medicinal Chemistry

2005

61

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