Concepedia

Sofiya Leshchenko

SL

7

Publications

958

Citations

7

H-Index

2004

Active since

Affiliations

University of Illinois Chicago(Current)

Georgia State University

Purdue University West Lafayette

Kumamoto University

Rosalind Franklin University of Medicine and Science

Sofiya Leshchenko is an author at University of Illinois Chicago specializing in structural biology, hiv, and natural sciences.

Top concepts

Publications per year

2004–2006

7

Publications

7

High Resolution Crystal Structures of HIV-1 Protease with a Potent Non-peptide Inhibitor (UIC-94017) Active Against Multi-drug-resistant Clinical Strains

Yunfeng Tie, Péter Boross, Yuan‐Fang Wang et al. · Journal of Molecular Biology · 2004 · 217 citations

, , +7

Structure-Based Design of Novel HIV-1 Protease Inhibitors To Combat Drug Resistance

Arun K. Ghosh, P. Sridhar, Sofiya Leshchenko et al. · Journal of Medicinal Chemistry · 2006 · 155 citations · Full text

Ultra-high Resolution Crystal Structure of HIV-1 Protease Mutant Reveals Two Binding Sites for Clinical Inhibitor TMC114

Andrey Kovalevsky, Fengling Liu, Sofiya Leshchenko et al. · Journal of Molecular Biology · 2006 · 143 citations · Full text

, , +7

Effectiveness of Nonpeptide Clinical Inhibitor TMC-114 on HIV-1 Protease with Highly Drug Resistant Mutations D30N, I50V, and L90M

Andrey Kovalevsky, Yunfeng Tie, Fengling Liu et al. · Journal of Medicinal Chemistry · 2006 · 142 citations · Full text

Stereoselective Photochemical 1,3-Dioxolane Addition to <i>5-</i>Alkoxymethyl-2(5<i>H</i>)-furanone:  Synthesis of Bis-tetrahydrofuranyl Ligand for HIV Protease Inhibitor UIC-94017 (TMC-114)

Arun K. Ghosh, Sofiya Leshchenko, Marcus W. Noetzel · The Journal of Organic Chemistry · 2004 · 134 citations

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