Haibo Yu

The Discovery and Characterization of ML218: A Novel, Centrally Active T-Type Calcium Channel Inhibitor with Robust Effects in STN Neurons and in a Rodent Model of Parkinson’s Disease

Zixiu Xiang, Analisa D. Thompson, John T. Brogan et al. · ACS Chemical Neuroscience · 2011 · 98 citations · Full text

Selective Inhibition of the K_ir2 Family of Inward Rectifier Potassium Channels by a Small Molecule Probe: The Discovery, SAR, and Pharmacological Characterization of ML133

Hao‐ran Wang, Meng Wu, Haibo Yu et al. · ACS Chemical Biology · 2011 · 97 citations

Pharmacological Characterization, Molecular Biology, Cellular Physiology +22

Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels

Haibo Yu, Zhihong Lin, Margrith E. Mattmann et al. · Proceedings of the National Academy of Sciences · 2013 · 89 citations · Full text

Four basic residues critical for the ion selectivity and pore blocker sensitivity of TMEM16A calcium-activated chloride channels

Christian J. Peters, Haibo Yu, Jason Tien et al. · Proceedings of the National Academy of Sciences · 2015 · 83 citations · Full text

Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective Kv7.1 (KCNQ1) potassium channel activator

Margrith E. Mattmann, Haibo Yu, Zhihong Lin et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 68 citations · Full text

Potassium Channel Activator, Biochemistry, Medicine +5