John T. Brogan

Antipsychotic Drug-Like Effects of the Selective M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator VU0152100

Nellie Byun, Michael Grannan, Michael Bubser et al. · Neuropsychopharmacology · 2014 · 119 citations · Full text

Psychiatry, Functional Selectivity, Medicine +9

The Discovery and Characterization of ML218: A Novel, Centrally Active T-Type Calcium Channel Inhibitor with Robust Effects in STN Neurons and in a Rodent Model of Parkinson’s Disease

Zixiu Xiang, Analisa D. Thompson, John T. Brogan et al. · ACS Chemical Neuroscience · 2011 · 98 citations · Full text

Chemical Modulation of Mutant mGlu₁ Receptors Derived from Deleterious <i>GRM1</i> Mutations Found in Schizophrenics

Hyekyung P. Cho, Pedro M. García-Barrantes, John T. Brogan et al. · ACS Chemical Biology · 2014 · 54 citations · Full text

Deleterious Nssnps, Synaptic Signaling, Social Sciences +17

Total Synthesis and Biological Evaluation of Phidianidines A and B Uncovers Unique Pharmacological Profiles at CNS Targets

John T. Brogan, Sydney L. Stoops, Craig W. Lindsley · ACS Chemical Neuroscience · 2012 · 47 citations · Full text

Bioorganic Chemistry, Indole Acetic Acids, Pharmacotherapy +21

Synthesis and Structure–Activity Relationships of Allosteric Potentiators of the M₄ Muscarinic Acetylcholine Receptor

J. Phillip Kennedy, Thomas M. Bridges, Patrick R. Gentry et al. · ChemMedChem · 2009 · 43 citations · Full text

Combinatorial Chemistry, Ec50 Values, Chemical Biology +18