L. Michelle Lewis

Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2

Eric Delpire, Emily Days, L. Michelle Lewis et al. · Proceedings of the National Academy of Sciences · 2009 · 143 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

A Novel Selective Muscarinic Acetylcholine Receptor Subtype 1 Antagonist Reduces Seizures without Impairing Hippocampus-Dependent Learning

Douglas J. Sheffler, Richard D. Williams, Thomas M. Bridges et al. · Molecular Pharmacology · 2009 · 133 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Discovery and Characterization of Novel Subtype-Selective Allosteric Agonists for the Investigation of M₁ Receptor Function in the Central Nervous System

Evan P. Lebois, Thomas M. Bridges, L. Michelle Lewis et al. · ACS Chemical Neuroscience · 2009 · 100 citations

Medicine, Neuroscience, Pharmacology +17

The Discovery and Characterization of ML218: A Novel, Centrally Active T-Type Calcium Channel Inhibitor with Robust Effects in STN Neurons and in a Rodent Model of Parkinson’s Disease

Zixiu Xiang, Analisa D. Thompson, John T. Brogan et al. · ACS Chemical Neuroscience · 2011 · 99 citations · Full text

Pharmacy, Neuroscience, Pharmacology +17

High-Throughput Screening Reveals a Small-Molecule Inhibitor of the Renal Outer Medullary Potassium Channel and Kir7.1

L. Michelle Lewis, Gautam Bhave, Brian A. Chauder et al. · Molecular Pharmacology · 2009 · 94 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17