Douglas J. Sheffler

Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates

Daniel F. Egan, Matthew G. H. Chun, Mitchell Vamos et al. · Molecular Cell · 2015 · 704 citations · Full text

Cell Autophagy, Mitophagy, Signal Transduction +12

mGluR5 Positive Allosteric Modulators Facilitate both Hippocampal LTP and LTD and Enhance Spatial Learning

Jennifer Ayala, Yelin Chen, Jessica L. Banko et al. · Neuropsychopharmacology · 2009 · 208 citations · Full text

Hippocampal Ltp, Functional Selectivity, Cortical Remodeling +7

Caveolin-1 Interacts with 5-HT2A Serotonin Receptors and Profoundly Modulates the Signaling of Selected Gαq-coupled Protein Receptors

Anushree Bhatnagar, Douglas J. Sheffler, Wesley K. Kroeze et al. · Journal of Biological Chemistry · 2004 · 167 citations · Full text

Synaptic Transmission, Neurotransmitter, Neurotransmission +20

A Novel Selective Muscarinic Acetylcholine Receptor Subtype 1 Antagonist Reduces Seizures without Impairing Hippocampus-Dependent Learning

Douglas J. Sheffler, Richard D. Williams, Thomas M. Bridges et al. · Molecular Pharmacology · 2009 · 132 citations · Full text

Novel Allosteric Agonists of M1 Muscarinic Acetylcholine Receptors Induce Brain Region-Specific Responses That Correspond with Behavioral Effects in Animal Models

Gregory J. Digby, Meredith J. Noetzel, Michael Bubser et al. · Journal of Neuroscience · 2012 · 111 citations · Full text