Mitchell Vamos

Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates

Daniel F. Egan, Matthew G. H. Chun, Mitchell Vamos et al. · Molecular Cell · 2015 · 704 citations · Full text

Cell Autophagy, Mitophagy, Signal Transduction +12

BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency

Lars Pache, Míriam Santos Dutra, Adam M. Spivak et al. · Cell Host & Microbe · 2015 · 145 citations · Full text

Viral Latency, Hiv-1 Transcription, Human Retrovirus +9

Design, Synthesis, and Characterization of an Orally Active Dual-Specific ULK1/2 Autophagy Inhibitor that Synergizes with the PARP Inhibitor Olaparib for the Treatment of Triple-Negative Breast Cancer

Huiyu Ren, Nicole A. Bakas, Mitchell Vamos et al. · Journal of Medicinal Chemistry · 2020 · 67 citations · Full text

Triggering necroptosis in cisplatin and IAP antagonist-resistant ovarian carcinoma

Katelyn E. McCabe, Karl Bacos, Dan Lü et al. · Cell Death and Disease · 2014 · 66 citations · Full text

Small-Molecule IAP Antagonists Sensitize Cancer Cells to TRAIL-Induced Apoptosis: Roles of XIAP and cIAPs

Darren Finlay, Mitchell Vamos, Marcos González‐López et al. · Molecular Cancer Therapeutics · 2013 · 51 citations · Full text

Signal Transduction, Signaling Pathway, Medicine +15