Hiroyuki Inuzuka

SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

Hiroyuki Inuzuka, Shavali Shaik, Ichiro Onoyama et al. · Nature · 2011 · 628 citations · Full text

Signaling Pathway, Cell Regulation, Apoptosis +6

Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy

Yang Gao, Naoe Taira Nihira, Xia Bu et al. · Nature Cell Biology · 2020 · 371 citations · Full text

Anti-pd-1 Immunotherapy, Cancer Immunosurveillance, Immunology +10

Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus

Pengda Liu, Michael J. Begley, Wojciech Michowski et al. · Nature · 2014 · 363 citations · Full text

Signal Transduction, Cell Regulation, Biochemistry +13

Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4

Xiangpeng Dai, Wenjian Gan, Xiaoning Li et al. · Nature Medicine · 2017 · 333 citations · Full text

Molecular Biology, Bet Inhibitors, Spop Mutations +6

STO-609, a Specific Inhibitor of the Ca2+/Calmodulin-dependent Protein Kinase Kinase

Hiroshi Tokumitsu, Hiroyuki Inuzuka, Yumi Ishikawa et al. · Journal of Biological Chemistry · 2002 · 285 citations · Full text