Naoe Taira Nihira

Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance

Jinfang Zhang, Xia Bu, Haizhen Wang et al. · Nature · 2017 · 1K citations · Full text

Tumor Biology, Cancer Immune Surveillance, Cancer Immunosurveillance +12

Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy

Yang Gao, Naoe Taira Nihira, Xia Bu et al. · Nature Cell Biology · 2020 · 371 citations · Full text

Anti-pd-1 Immunotherapy, Cancer Immunosurveillance, Immunology +10

G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells

Lijun Liu, Wojciech Michowski, Hiroyuki Inuzuka et al. · Nature Cell Biology · 2017 · 131 citations · Full text

Embryonic Stem Cell, Induced Pluripotent Stem Cell, Developmental Biology +11

Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function

Naoe Taira Nihira, Kohei Ogura, Kouhei Shimizu et al. · Science Signaling · 2017 · 79 citations · Full text

The SCF ^β-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis

Kouhei Shimizu, Hidefumi Fukushima, Kohei Ogura et al. · Science Signaling · 2017 · 54 citations