Jinfang Zhang

Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance

Jinfang Zhang, Xia Bu, Haizhen Wang et al. · Nature · 2017 · 1K citations · Full text

Medicine, Cancer Biology, Oncology +17

Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy

Yang Gao, Naoe Taira Nihira, Xia Bu et al. · Nature Cell Biology · 2020 · 393 citations · Full text

Medicine, Cancer Biology, Oncology +16

PtdIns(3,4,5) <i>P</i> 3-Dependent Activation of the mTORC2 Kinase Complex

Pengda Liu, Wenjian Gan, Y. Rebecca Chin et al. · Cancer Discovery · 2015 · 377 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4

Xiangpeng Dai, Wenjian Gan, Xiaoning Li et al. · Nature Medicine · 2017 · 340 citations · Full text

Medicine, Molecular Biology, Oncology +8

Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway

Yu-Ru Lee, Ming Chen, Jonathan D. Lee et al. · Science · 2019 · 340 citations

Medicine, Molecular Biology, Oncology +17