Pengda Liu

CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1

Bartlomiej Bartkowiak, Pengda Liu, Hemali Phatnani et al. · Genes & Development · 2010 · 401 citations · Full text

Life Sciences, Genetics, Molecular Biology +10

PtdIns(3,4,5) <i>P</i> 3-Dependent Activation of the mTORC2 Kinase Complex

Pengda Liu, Wenjian Gan, Y. Rebecca Chin et al. · Cancer Discovery · 2015 · 377 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus

Pengda Liu, Michael J. Begley, Wojciech Michowski et al. · Nature · 2014 · 367 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4

Xiangpeng Dai, Wenjian Gan, Xiaoning Li et al. · Nature Medicine · 2017 · 340 citations · Full text

Medicine, Molecular Biology, Oncology +8

Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis

Pengda Liu, Wenjian Gan, Hiroyuki Inuzuka et al. · Nature Cell Biology · 2013 · 257 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13