Ichiro Onoyama

SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

Hiroyuki Inuzuka, Shavali Shaik, Ichiro Onoyama et al. · Nature · 2011 · 628 citations · Full text

Signaling Pathway, Cell Regulation, Apoptosis +6

p57 Is Required for Quiescence and Maintenance of Adult Hematopoietic Stem Cells

Akinobu Matsumoto, Shoichiro Takeishi, Tomoharu Kanie et al. · Cell stem cell · 2011 · 310 citations · Full text

Developmental Biology, Medicine, Stem Cell Mobilization +7

Ablation of Fbxw7 Eliminates Leukemia-Initiating Cells by Preventing Quiescence

Shoichiro Takeishi, Akinobu Matsumoto, Ichiro Onoyama et al. · Cancer Cell · 2013 · 185 citations · Full text

Hematological Malignancy, Cell Death, Cellular Senescence +4

Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL

Sahoko Matsuoka, Yuichi Oike, Ichiro Onoyama et al. · Genes & Development · 2008 · 181 citations · Full text

Cell Therapy, Immunology, Cell Death +20

<i>p53</i> -Altered <i>FBXW7</i> Expression Determines Poor Prognosis in Gastric Cancer Cases

Takehiko Yokobori, Koshi Mimori, Masaaki Iwatsuki et al. · Cancer Research · 2009 · 177 citations · Full text