Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

Tohru Kitada, Shuichi Asakawa, Nobutaka Hattori, +5

Nature

Molecular NeuroscienceMendelian DisorderGenetic DisorderGeneticsParkinson Disease +5

Loss of autophagy in the central nervous system causes neurodegeneration in mice

Masaaki Komatsu, Satoshi Waguri, Tomoki Chiba, +8

Nature

Cell AutophagyNeurodegenerative DiseasesMitophagyAutophagyCell Death +10

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹

Daniel J. Klionsky, Amal Kamal Abdel‐Aziz, Sara Abdelfatah, +1267

Autophagy

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

Masaaki Komatsu, H. Kurokawa, Satoshi Waguri, +16

Nature Cell Biology

Cell AutophagyMitophagySignal TransductionSignaling PathwayCell Regulation +8

Impairment of starvation-induced and constitutive autophagy in <i>Atg7</i> -deficient mice

Masaaki Komatsu, Satoshi Waguri, Takashi Ueno, +10

The Journal of Cell Biology

A cross-population atlas of genetic associations for 220 human phenotypes

Saori Sakaue, Masahiro Kanai, Yosuke Tanigawa, +26

Nature Genetics

Genome-wide Association StudyHaplotype DeterminationHuman PhenotypesGenotype-phenotype AssociationHuman Variation +6

Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice

Masaaki Komatsu, Satoshi Waguri, Masato Koike, +22

Cell

Cell AutophagyMitophagyDevelopmental BiologyAutophagy-deficient MiceAutophagy +8

A ubiquitin-like system mediates protein lipidation

Yoshinobu Ichimura, Takayoshi Kirisako, Toshifumi Takao, +9

Nature

Protein FunctionBiochemistryNatural SciencesProtein LipidationCellular Biochemistry +1

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

Hideki Shimura, Nobutaka Hattori, Shinichiro Kubo, +7

Nature Genetics

Ubiquitin-protein LigaseMendelian DisorderGeneticsMolecular BiologyNeurochemical Biomarkers +3

ISTH interim guidance on recognition and management of coagulopathy in COVID‐19

Jecko Thachil, Ning Tang, Satoshi Gando, +5

Journal of Thrombosis and Haemostasis

ThrombosisClinical Infectious DiseaseCovid-19 PandemicHematologyHemostasis +7