Charles A. Gersbach

Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers

Isaac B. Hilton, Anthony D’Ippolito, Christopher M. Vockley et al. · Nature Biotechnology · 2015 · 1.9K citations · Full text

Life Sciences, Genetics, Molecular Biology +13

RNA-guided gene activation by CRISPR-Cas9–based transcription factors

Pablo Pérez‐Piñera, D. Dewran Koçak, Christopher M. Vockley et al. · Nature Methods · 2013 · 1.3K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +16

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy

Christopher E. Nelson, Chady H. Hakim, David G. Ousterout et al. · Science · 2015 · 1.1K citations

Life Sciences, Genetics, Molecular Biology +17

Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements

Pratiksha I. Thakore, Anthony D’Ippolito, Lingyun Song et al. · Nature Methods · 2015 · 1K citations

Life Sciences, Genetics, Molecular Biology +16

A light-inducible CRISPR-Cas9 system for control of endogenous gene activation

Lauren R. Polstein, Charles A. Gersbach · Nature Chemical Biology · 2015 · 651 citations · Full text

Life Sciences, Genetics, Molecular Biology +11