Chady H. Hakim

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy

Christopher E. Nelson, Chady H. Hakim, David G. Ousterout et al. · Science · 2015 · 1.1K citations

Life Sciences, Genetics, Molecular Biology +17

Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models

Chady H. Hakim, Sandeep Kumar, Dennis O. Pérez‐López et al. · Nature Communications · 2021 · 170 citations · Full text

Life Sciences, Immunology, Molecular Genetics +16

Microdystrophin Ameliorates Muscular Dystrophy in the Canine Model of Duchenne Muscular Dystrophy

Jin‐Hong Shin, Xiufang Pan, Chady H. Hakim et al. · Molecular Therapy · 2013 · 131 citations · Full text

Medicine, Molecular Genetics, Neurology +14

Safe and bodywide muscle transduction in young adult Duchenne muscular dystrophy dogs with adeno-associated virus

Yongping Yue, Xiufang Pan, Chady H. Hakim et al. · Human Molecular Genetics · 2015 · 117 citations · Full text

Medicine, Molecular Medicine, Veterinary Clinical Sciences +15

A Five-Repeat Micro-Dystrophin Gene Ameliorated Dystrophic Phenotype in the Severe DBA/2J-mdx Model of Duchenne Muscular Dystrophy

Chady H. Hakim, Nalinda B. Wasala, Xiufang Pan et al. · Molecular Therapy — Methods & Clinical Development · 2017 · 109 citations · Full text

Medicine, Genetics, Molecular Genetics +11