David G. Ousterout

RNA-guided gene activation by CRISPR-Cas9–based transcription factors

Pablo Pérez‐Piñera, D. Dewran Koçak, Christopher M. Vockley et al. · Nature Methods · 2013 · 1.3K citations · Full text

Transcriptional Regulation, Natural Sciences, Molecular Biology +6

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy

Christopher E. Nelson, Chady H. Hakim, David G. Ousterout et al. · Science · 2015 · 1.1K citations · Full text

Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy

David G. Ousterout, Ami M. Kabadi, Pratiksha I. Thakore et al. · Nature Communications · 2015 · 448 citations · Full text

Dmd Mutations, Crispr/cas9 Genome-editing Platform, Genetics +18

Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector

Ami M. Kabadi, David G. Ousterout, Isaac B. Hilton et al. · Nucleic Acids Research · 2014 · 378 citations · Full text

Genetics, Multiplex Gene, Molecular Biology +17

Synergistic and tunable human gene activation by combinations of synthetic transcription factors

Pablo Pérez‐Piñera, David G. Ousterout, Jonathan M. Brunger et al. · Nature Methods · 2013 · 238 citations

Transcriptional Regulation, Transcription Factors, Natural Sciences +14