D. Dewran Koçak

RNA-guided gene activation by CRISPR-Cas9–based transcription factors

Pablo Pérez‐Piñera, D. Dewran Koçak, Christopher M. Vockley et al. · Nature Methods · 2013 · 1.3K citations · Full text

Transcriptional Regulation, Natural Sciences, Molecular Biology +6

Increasing the specificity of CRISPR systems with engineered RNA secondary structures

D. Dewran Koçak, Eric A. Josephs, Vidit Bhandarkar et al. · Nature Biotechnology · 2019 · 350 citations

Engineering, Genetics, Rna Biology +9

Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage

Eric A. Josephs, D. Dewran Koçak, Christopher J. Fitzgibbon et al. · Nucleic Acids Research · 2015 · 151 citations · Full text

Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators

Lauren R. Polstein, Pablo Pérez‐Piñera, D. Dewran Koçak et al. · Genome Research · 2015 · 128 citations · Full text

Genetics, Molecular Biology, Epigenetics +23

Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding

Ian C. McDowell, Alejandro Barrera, Anthony D’Ippolito et al. · Genome Research · 2018 · 124 citations · Full text

Epigenetic Change, Genetics, Motif-directed Binding +22