Pratiksha I. Thakore

Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers

Isaac B. Hilton, Anthony D’Ippolito, Christopher M. Vockley et al. · Nature Biotechnology · 2015 · 1.8K citations · Full text

Natural Sciences, Genetics, Epigenome Editing +10

RNA-guided gene activation by CRISPR-Cas9–based transcription factors

Pablo Pérez‐Piñera, D. Dewran Koçak, Christopher M. Vockley et al. · Nature Methods · 2013 · 1.3K citations · Full text

Transcriptional Regulation, Natural Sciences, Molecular Biology +6

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy

Christopher E. Nelson, Chady H. Hakim, David G. Ousterout et al. · Science · 2015 · 1.1K citations · Full text

Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements

Pratiksha I. Thakore, Anthony D’Ippolito, Lingyun Song et al. · Nature Methods · 2015 · 1K citations · Full text

Transcriptional Regulation, Off-target Effect, Medicine +14

Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells

Eleni P. Mimitou, Caleb A. Lareau, Kelvin Y. Chen et al. · Nature Biotechnology · 2021 · 516 citations · Full text

Bioinformatics, Chromatin, Chromatin Accessibility +14