Concepedia

A light-inducible CRISPR-Cas9 system for control of endogenous gene activation

Lauren R. Polstein, Charles A. Gersbach

Nature Chemical Biology · 2015 · 651 citations · 24 references

DOIFull text

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Concepts

References

24

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text

, , +17

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

Lei S. Qi, Matthew H. Larson, Luke A. Gilbert et al. · Cell · 2013 · 5.2K citations · Full text

, , +16

CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

Luke A. Gilbert, Matthew H. Larson, Leonardo Morsut et al. · Cell · 2013 · 3.8K citations · Full text

, , +12

A TALE nuclease architecture for efficient genome editing

Jeffrey C. Miller, Siyuan Tan, Guijuan Qiao et al. · Nature Biotechnology · 2010 · 2.1K citations

, , +14

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

Prashant Mali, John Aach, P. Benjamin Stranges et al. · Nature Biotechnology · 2013 · 1.8K citations · Full text

, , +14