Ann Aulabaugh

Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery

Mei-Chu Lo, Ann Aulabaugh, Guixian Jin et al. · Analytical Biochemistry · 2004 · 675 citations

Drug Target, Engineering, Hit Identification +11

Chemical and Computational Methods for the Characterization of Covalent Reactive Groups for the Prospective Design of Irreversible Inhibitors

Mark E. Flanagan, J. A. Abramite, Dennis P. Anderson et al. · Journal of Medicinal Chemistry · 2014 · 318 citations

Combinatorial Chemistry, Drug Target, Thiol-reactive Covalent Inhibitors +17

Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay

J. Perry Hall, Amy Brault, Fabien Vincent et al. · PLoS ONE · 2017 · 157 citations · Full text

Oxalyl hydroxamates as reaction-intermediate analogs for ketol-acid reductoisomerase

Ann Aulabaugh, John V. Schloss · Biochemistry · 1990 · 106 citations

Acylguanidines as Small-Molecule β-Secretase Inhibitors

Derek C. Cole, Eric S. Manas, Joseph R. Stock et al. · Journal of Medicinal Chemistry · 2006 · 100 citations · Full text

Protein Assembly, Molecular Biology, Amyloid Precursor Protein +20