Derek C. Cole

Recent stereoselective synthetic approaches to β-amino acids

Derek C. Cole · Tetrahedron · 1994 · 456 citations

β-Amino Acids, Bioorganic Chemistry, Biochemistry +3

Biochemical, Cellular, and <i>In vivo</i> Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin

Ker Yu, Lourdes Toral‐Barza, Celine Shi et al. · Cancer Research · 2009 · 326 citations

Chemoprevention Strategy, Cellular Pharmacology, Selective Inhibitors +22

Design, Synthesis, and Biological Activity of a Potent Inhibitor of the Neuropeptidase N-Acetylated α-Linked Acidic Dipeptidase

Paul Jackson, Derek C. Cole, Barbara S. Slusher et al. · Journal of Medicinal Chemistry · 1996 · 251 citations · Full text

Neuropharmacological Profile of Novel and Selective 5-HT6 Receptor Agonists: WAY-181187 and WAY-208466

Lee E. Schechter, Qian Lin, Deborah L. Smith et al. · Neuropsychopharmacology · 2007 · 217 citations · Full text

Neuropharmacological Profile, Functional Selectivity, Medicine +9

Discovery of Begacestat, a Notch-1-Sparing γ-Secretase Inhibitor for the Treatment of Alzheimer’s Disease

Scott C. Mayer, Anthony F. Kreft, Boyd L. Harrison et al. · Journal of Medicinal Chemistry · 2008 · 109 citations · Full text

Stable Analogue 10, Alzheimer ’, Social Sciences +19