Scott C. Mayer

Begacestat (GSI-953): A Novel, Selective Thiophene Sulfonamide Inhibitor of Amyloid Precursor Protein γ-Secretase for the Treatment of Alzheimer’s Disease

Robert Martone, Hua Zhou, Kevin Atchison et al. · Journal of Pharmacology and Experimental Therapeutics · 2009 · 157 citations

Discovery of Begacestat, a Notch-1-Sparing γ-Secretase Inhibitor for the Treatment of Alzheimer’s Disease

Scott C. Mayer, Anthony F. Kreft, Boyd L. Harrison et al. · Journal of Medicinal Chemistry · 2008 · 109 citations · Full text

Stable Analogue 10, Alzheimer ’, Social Sciences +19

Pharmacological comparison of muscarinic ligands: Historical versus more recent muscarinic M1-preferring receptor agonists

Julia Heinrich, John A. Butera, Tikva Carrick et al. · European Journal of Pharmacology · 2009 · 98 citations

Historical Versus, Functional Selectivity, Medicine +9

Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment

Scott C. Mayer, A. Banker, Frank Boschelli et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 67 citations · Full text

Medicinal Chemistry, Medicine, Isoquinolinedione Inhibitors +9

Synthesis of New Didemnin B Analogs for Investigations of Structure/Biological Activity Relationships

Scott C. Mayer, Joshi M. Ramanjulu, Matthew D. Vera et al. · The Journal of Organic Chemistry · 1994 · 67 citations

Molecular Sciences, Structure/biological Activity Relationships, Molecular Diversity +15