Concepedia

Hua Zhou

HZ

Statistics

Publications

34

Citations

1.3K

H-Index

19

Active since

2005

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

Princeton University

Quantitative BioSciences

Shandong University

Jiangxi Agricultural University

Hua Zhou is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in drug discovery, medicinal chemistry, and pharmacology.

ORCID

Publications per year

2005–2024

34

Publications

34

Begacestat (GSI-953): A Novel, Selective Thiophene Sulfonamide Inhibitor of Amyloid Precursor Protein γ-Secretase for the Treatment of Alzheimer’s Disease

Robert Martone, Hua Zhou, Kevin Atchison et al. · Journal of Pharmacology and Experimental Therapeutics · 2009 · 157 citations

, , +17

Enhanced clearance of Aβ in brain by sustaining the plasmin proteolysis cascade

J. Steven Jacobsen, Thomas A. Comery, Robert Martone et al. · Proceedings of the National Academy of Sciences · 2008 · 140 citations · Full text

, , +17

Discovery of Begacestat, a Notch-1-Sparing γ-Secretase Inhibitor for the Treatment of Alzheimer’s Disease

Scott C. Mayer, Anthony F. Kreft, Boyd L. Harrison et al. · Journal of Medicinal Chemistry · 2008 · 111 citations · Full text

, , +15

Discovery of Potent and Orally Available Bicyclo[1.1.1]pentane-Derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors

Qinglin Pu, Hongjun Zhang, Liangqin Guo et al. · ACS Medicinal Chemistry Letters · 2020 · 87 citations · Full text

, , +12

Advances in the Chemistry of Quinoxalinone Derivatives

Leilei Shi, Hua Zhou, Jifeng Wu et al. · Mini-Reviews in Organic Chemistry · 2014 · 78 citations

, , +14

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