J. A. Abramite

Chemical and Computational Methods for the Characterization of Covalent Reactive Groups for the Prospective Design of Irreversible Inhibitors

Mark E. Flanagan, J. A. Abramite, Dennis P. Anderson et al. · Journal of Medicinal Chemistry · 2014 · 318 citations

Combinatorial Chemistry, Drug Target, Thiol-reactive Covalent Inhibitors +17

A Site-Selective Dual Anchoring Strategy for Artificial Metalloprotein Design

James R. Carey, K Butler Steven, Thomas D. Pfister et al. · Journal of the American Chemical Society · 2004 · 240 citations

Dual Anchoring Attachments, Protein Assembly, Molecular Biology +16

Pyridone Methylsulfone Hydroxamate LpxC Inhibitors for the Treatment of Serious Gram-Negative Infections

Justin I. Montgomery, Matthew F. Brown, Usa Reilly et al. · Journal of Medicinal Chemistry · 2012 · 97 citations · Full text

Pharmaceutical Science, Pharmacotherapy, New Series +19

Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections

Matthew F. Brown, Usa Reilly, J. A. Abramite et al. · Journal of Medicinal Chemistry · 2011 · 97 citations · Full text

Discovery of Dap-3 Polymyxin Analogues for the Treatment of Multidrug-Resistant Gram-Negative Nosocomial Infections

Thomas V. Magee, Matthew F. Brown, Jeremy T. Starr et al. · Journal of Medicinal Chemistry · 2013 · 55 citations

Vitro Potency, Novel Polymyxin Analogues, Health Sciences +15