Mei-Chu Lo

Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery

Mei-Chu Lo, Ann Aulabaugh, Guixian Jin et al. · Analytical Biochemistry · 2004 · 675 citations

Drug Target, Engineering, Hit Identification +11

Discovery of AMG 232, a Potent, Selective, and Orally Bioavailable MDM2–p53 Inhibitor in Clinical Development

Daqing Sun, Zhihong Li, Yosup Rew et al. · Journal of Medicinal Chemistry · 2014 · 290 citations · Full text

A “Click Chemistry Platform” for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation

Ryan P. Wurz, Ken Dellamaggiore, Hannah Dou et al. · Journal of Medicinal Chemistry · 2017 · 196 citations

Bispecific Molecules, Protein Assembly, Molecular Biology +17

Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction

Yosup Rew, Daqing Sun, Felix González-López de Turiso et al. · Journal of Medicinal Chemistry · 2012 · 166 citations · Full text

Selective and Potent Morpholinone Inhibitors of the MDM2–p53 Protein–Protein Interaction

Ana Z. González, John Eksterowicz, Michael D. Bartberger et al. · Journal of Medicinal Chemistry · 2014 · 83 citations · Full text