Felix González-López de Turiso

Discovery of AMG 232, a Potent, Selective, and Orally Bioavailable MDM2–p53 Inhibitor in Clinical Development

Daqing Sun, Zhihong Li, Yosup Rew et al. · Journal of Medicinal Chemistry · 2014 · 290 citations · Full text

Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction

Yosup Rew, Daqing Sun, Felix González-López de Turiso et al. · Journal of Medicinal Chemistry · 2012 · 166 citations · Full text

Radical Cyclization Approach to Spirocyclohexadienones

Felix González-López de Turiso, Dennis P. Curran · Organic Letters · 2004 · 116 citations

Medicinal Chemistry, Aryl Radical, Natural Sciences +13

Discovery and in Vivo Evaluation of (<i>S</i>)-<i>N</i>-(1-(7-Fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9<i>H</i>-purin-6-amine (AMG319) and Related PI3Kδ Inhibitors for Inflammation and Autoimmune Disease

Timothy D. Cushing, Xiaolin Hao, Youngsook Shin et al. · Journal of Medicinal Chemistry · 2014 · 84 citations

Pharmaceutical Science, Immune Regulation, Immunology +23

Rational Design and Binding Mode Duality of MDM2–p53 Inhibitors

Felix González-López de Turiso, Daqing Sun, Yosup Rew et al. · Journal of Medicinal Chemistry · 2013 · 83 citations · Full text

Potent Mdm2 Inhibitors, Drug Target, Molecular Biology +17