Ryan P. Wurz

Discovery of a Covalent Inhibitor of KRAS^G12C (AMG 510) for the Treatment of Solid Tumors

Brian A. Lanman, Jennifer R. Allen, John G. Allen et al. · Journal of Medicinal Chemistry · 2019 · 677 citations · Full text

Drug Target, Solid Tumors, Molecular Biology +20

Catalytic Asymmetric Synthesis of Piperidine Derivatives through the [4 + 2] Annulation of Imines with Allenes

Ryan P. Wurz, Gregory C. Fu · Journal of the American Chemical Society · 2005 · 375 citations

Asymmetric Catalysis, Chemical Engineering, Catalytic Asymmetric Synthesis +14

Photoinduced, Copper-Catalyzed Decarboxylative C–N Coupling to Generate Protected Amines: An Alternative to the Curtius Rearrangement

Wei Zhao, Ryan P. Wurz, Jonas C. Peters et al. · Journal of the American Chemical Society · 2017 · 317 citations · Full text

TBK1 Directly Engages Akt/PKB Survival Signaling to Support Oncogenic Transformation

Yi-Hung Ou, Michael J. Torres, Rosalyn Ram et al. · Molecular Cell · 2011 · 227 citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +7

Doubly Activated Cyclopropanes as Synthetic Precursors for the Preparation of 4-Nitro- and 4-Cyano-dihydropyrroles and Pyrroles

Ryan P. Wurz, André B. Charette · Organic Letters · 2005 · 210 citations

Situ-generated Phenyliodonium Ylides, Chemical Engineering, 1-Cyano-cyclopropyl Ketones +15