Ryan P. Wurz

Discovery of a Covalent Inhibitor of KRAS^G12C (AMG 510) for the Treatment of Solid Tumors

Brian A. Lanman, Jennifer R. Allen, John G. Allen et al. · Journal of Medicinal Chemistry · 2019 · 722 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +16

Catalytic Asymmetric Synthesis of Piperidine Derivatives through the [4 + 2] Annulation of Imines with Allenes

Ryan P. Wurz, Gregory C. Fu · Journal of the American Chemical Society · 2005 · 377 citations

Natural Sciences, Chemistry, Medicinal Chemistry +14

Photoinduced, Copper-Catalyzed Decarboxylative C–N Coupling to Generate Protected Amines: An Alternative to the Curtius Rearrangement

Wei Zhao, Ryan P. Wurz, Jonas C. Peters et al. · Journal of the American Chemical Society · 2017 · 320 citations · Full text

Natural Sciences, Chemistry, Catalysis +16

TBK1 Directly Engages Akt/PKB Survival Signaling to Support Oncogenic Transformation

Yi-Hung Ou, Michael J. Torres, Rosalyn Ram et al. · Molecular Cell · 2011 · 229 citations · Full text

Medicine, Cancer Biology, Molecular Biology +14

Doubly Activated Cyclopropanes as Synthetic Precursors for the Preparation of 4-Nitro- and 4-Cyano-dihydropyrroles and Pyrroles

Ryan P. Wurz, André B. Charette · Organic Letters · 2005 · 213 citations

Natural Sciences, Chemistry, Catalysis +10