Nature Biotechnology · 2022 · 222 citations · 41 references
Life SciencesBiotechnologyMolecular BiologyDna RepairGenetic EngineeringGenome EngineeringDna Double-strand Break RepairDouble-strand Break RepairGenetic Engineering Of CellsHomologous RecombinationNucleic Acid EngineeringSingle-strand Break RepairDna Repair Pathway EngineeringDna Repair Pathway ModulationDouble-strand Break End ProcessingPrimary CellsSingle-stranded Oligodeoxynucleotide Repair
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Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma
Nikhil C. Munshi, Larry D. Anderson, Nina Shah et al. · New England Journal of Medicine · 2021 · 2.4K citations · Full text
Medicine, Hematology, Oncology +17
CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia
Haydar Frangoul, David Altshuler, Maria Domenica Cappellini et al. · New England Journal of Medicine · 2020 · 1.9K citations · Full text
Life Sciences, Genetics, Hematology +17
Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
Justin Eyquem, Jorge Mansilla‐Soto, Theodoros Giavridis et al. · Nature · 2017 · 1.8K citations · Full text
CRISPR-engineered T cells in patients with refractory cancer
Edward A. Stadtmauer, Joseph A. Fraietta, Megan M. Davis et al. · Science · 2020 · 1.4K citations · Full text
Accurate classification of BRCA1 variants with saturation genome editing
Gregory M. Findlay, Riza M. Daza, Beth Martin et al. · Nature · 2018 · 924 citations · Full text