Eric Shifrut

Reprogramming human T cell function and specificity with non-viral genome targeting

Theodore L. Roth, Cristina Puig-Saus, Ruby Yu et al. · Nature · 2018 · 817 citations · Full text

Immunological Memory, Non-viral Genome Targeting, Adaptive Immune System +9

McPAS-TCR: a manually curated catalogue of pathology-associated T cell receptor sequences

Nili Tickotsky, Tal Sagiv, Jaime Prilusky et al. · Bioinformatics · 2017 · 548 citations · Full text

Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function

Eric Shifrut, Julia Carnevale, Victoria Tobin et al. · Cell · 2018 · 536 citations · Full text

Immunological Memory, Autoimmune Disease, Adaptive Immune System +11

Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence

Julia A. Belk, Winnie Yao, Nghi Ly et al. · Cancer Cell · 2022 · 316 citations · Full text

Chromatin, Chromatin Remodeling, Genetics +9

Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency

David N. Nguyen, Theodore L. Roth, P. Jonathan Li et al. · Nature Biotechnology · 2019 · 307 citations · Full text

Genome Editing Efficiency, Repair Templates, Engineering +10