Concepedia

Double-strand Break End Processing

Double-Strand Break End Processing is a molecular mechanism within the broader category of DNA repair processes that specifically involves the enzymatic modification of broken DNA ends to generate 3′ single-stranded overhangs required for homologous recombination during homology-directed repair.

126

Publications

11.1K

Citations

560

Authors

251

Institutions

Publications per year

2017–2026

20

Parents

Publications

126

Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends

Zhu Zhu, Woo-Hyun Chung, Eun Yong Shim et al. · Cell · 2008 · 1K citations · Full text

, , +13

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

Eleni P. Mimitou, Lorraine S. Symington · Nature · 2008 · 997 citations

, , +8

A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae

Liang Cao, Eric Alani, Nancy Kleckner · Cell · 1990 · 686 citations

, , +16

Endonucleolytic processing of covalent protein-linked DNA double-strand breaks

Matthew J. Neale, Jing Pan, Scott Keeney · Nature · 2005 · 614 citations · Full text

, , +14

Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks

Martin R. Singleton, Mark S. Dillingham, Martin Gaudier et al. · Nature · 2004 · 433 citations

, , +16

1–5 of 126

Authors

560

  1. DA
    Dale A. Ramsden

    University of North Carolina at Chapel Hill, United States

    4 publications · 810 citations

    4

    h-index

  2. PS
    Patrick Sung

    Yale University, United States

    4 publications · 139 citations

    4

    h-index

  3. TL
    Tom L. Blundell

    University of Cambridge, United Kingdom

    3 publications · 80 citations

    3

    h-index

  4. ML
    Markus Löbrich

    Technische Universität Darmstadt, Germany

    4 publications · 323 citations

    3

    h-index

  5. SP
    Susan P. Lees‐Miller

    University of Calgary, Canada

    3 publications · 350 citations

    3

    h-index

1–5 of 560

Institutions

251

  1. Harvard University

    Cambridge, United States

    5 h-index

    9 publications

    2.2K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    5 h-index

    17 publications

    1.5K citations

  3. National Institutes of Health

    Bethesda, United States

    5 h-index

    14 publications

    667 citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    23 publications

    2.3K citations

  5. National Institute of Environmental Health Sciences

    Durham, United States

    4 h-index

    12 publications

    360 citations

  6. University of New Mexico

    Albuquerque, United States

    4 h-index

    11 publications

    521 citations

  7. Yale University

    New Haven, United States

    4 h-index

    13 publications

    632 citations

  8. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    4 h-index

    13 publications

    2.4K citations

1–8 of 251

Venues

  1. Nucleic Acids Research

    13 publications · 640 citations

    13

    h-index

  2. Journal of Biological Chemistry

    JBC · 11 publications · 974 citations

    11

    h-index

  3. DNA repair

    9 publications · 263 citations

    9

    h-index

  4. Molecular Cell

    8 publications · 985 citations

    8

    h-index

  5. Molecular and Cellular Biology

    MCB · 6 publications · 705 citations

    6

    h-index

1–5