Concepedia

The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis

Eunüs S. Ali, Anna Lipońska, Brendan P. O’Hara, David R. Amici, Michael D. Torno, Peng Gao, John M. Asara, Mee‐Ngan F. Yap, Marc L. Mendillo, Issam Ben‐Sahra

Molecular Cell · 2022 · 40 citations · 44 references

DOIFull text

Open access

Concepts

References

44

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text

, , +14

ViennaRNA Package 2.0

Ronny Lorenz, Christian Höner zu Siederdissen, Hakim Tafer et al. · Algorithms for Molecular Biology · 2011 · 5.4K citations · Full text

, , +17

Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells

Robin M. Meyers, Jordan Bryan, James M. McFarland et al. · Nature Genetics · 2017 · 2.2K citations · Full text

, , +15

A unifying model for mTORC1-mediated regulation of mRNA translation

Carson C. Thoreen, Lynne Chantranupong, Heather R. Keys et al. · Nature · 2012 · 1.5K citations · Full text

, , +16

mTOR and S6K1 Mediate Assembly of the Translation Preinitiation Complex through Dynamic Protein Interchange and Ordered Phosphorylation Events

Marina K. Holz, Bryan A. Ballif, Steven P. Gygi et al. · Cell · 2005 · 1.2K citations · Full text

, , +17