Protein Translation

Protein translation is a cellular process in which ribosomes decode the nucleotide sequence of messenger RNA to synthesize proteins by catalyzing the sequential formation of peptide bonds between amino acids delivered by transfer RNAs.

35.7K

Publications

2.6M

Citations

87.1K

Authors

6.5K

Institutions

Publications per year

2017–2026

3.7K

Variants

Translation

Parents

Molecular Biology

Children

Aminoacyl-transfer Ribonucleic Acid (Trna) ChargingCo-translational Protein FoldingCo-translational TargetingCodon RecognitionGenetic CodeReading Frame SelectionRibosome AssemblyRibosome BiogenesisRibosome FunctionRibosome Recycling

Publications

35.7K

Protein production by auto-induction in high-density shaking cultures

F. William Studier · Protein Expression and Purification · 2005 · 6.1K citations

Life Sciences, Biochemistry, Biotechnology +12

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

Marilyn Kozak · Cell · 1986 · 4.9K citations

Life Sciences, Genetics, Molecular Biology +14

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

Frank L. Graham, W. C. Russell, James R. Smiley et al. · Journal of General Virology · 1977 · 4.9K citations

Life Sciences, Molecular Biology, Molecular Genetics +16

Global analysis of protein localization in budding yeast

Won‐Ki Huh, James V. Falvo, Luke C. Gerke et al. · Nature · 2003 · 4.4K citations

Life Sciences, Cell Biology, Molecular Biology +14

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

Gray D. Shaw, Robert Kamen · Cell · 1986 · 4.1K citations

Life Sciences, Genetics, Molecular Biology +14

1–5 of 35.7K

Authors

87.1K

NS
Nahum Sonenberg
McGill University, Canada
238 publications · 41.5K citations
113
h-index
JW
John W.B. Hershey
University of California, Davis, United States
138 publications · 13.8K citations
70
h-index
MV
Marina V. Rodnina
Max Planck Institute for Biophysical Chemistry, Germany
119 publications · 13.2K citations
64
h-index
AG
Alan G. Hinnebusch
Eunice Kennedy Shriver National Institute of Child Health and Human Development, United States
119 publications · 11.1K citations
63
h-index
LS
Leonard S. Jefferson
Pennsylvania State University, United States
112 publications · 11.6K citations
62
h-index

1–5 of 87.1K

Institutions

6.5K

1–8 of 6.5K

Venues

Proceedings of the National Academy of Sciences
PNAS · 2.3K publications · 263.6K citations
233
h-index
Journal of Biological Chemistry
JBC · 3.6K publications · 274.7K citations
197
h-index
Cell
362 publications · 107.2K citations
189
h-index
Nature
537 publications · 109.7K citations
179
h-index
Science
341 publications · 87.6K citations
167
h-index

1–5

See also Protein Translation
Core Mechanisms	Translation Initiation Translation Termination Translation Elongation Ribosomal Translocation Internal Ribosome Entry Sites Translation Reinitiation
Key Components	Aminoacyl-trna Synthetases Ribosome Biogenesis Transfer Rna Biochemistry Messenger Rna Structure Ribosomal Rnas Trna Binding Sites Translation Factors Orthogonal Ribosomes Orthogonal Aminoacyl-transfer Ribonucleic Acid Synthetases
Regulation	Cap-dependent Translation Initiation Trna Availability Translational Reprogramming Rna Modification Initiation Factor Phosphorylation Nonsense-mediated Mrna Decay No-go Mrna Decay
Errors and Fidelity	Aminoacyl-trna Synthetases Ribosome-mediated Translational Arrest Programmed Ribosomal Frameshifting Stop Codon Readthrough No-go Mrna Decay Nonsense-mediated Decay Ribosome-associated Quality Control
Variants	Chloroplast Translation Archaeal Translation Prokaryotic Translation Regulation