Concepedia

Translation Reinitiation

Translation Reinitiation is a mechanism in eukaryotic translation initiation whereby a ribosome that has terminated translation of an upstream open reading frame subsequently reinitiates translation at a downstream start codon on the same mRNA, enabled by specific cis-acting elements and trans-acting factors that distinguish it from de novo initiation.

124

Publications

11.9K

Citations

430

Authors

169

Institutions

Publications per year

2017–2026

18

Parents

Publications

124

Reinitiation involving upstream ORFs regulates <i>ATF4</i> mRNA translation in mammalian cells

Krishna M. Vattem, Ronald C. Wek · Proceedings of the National Academy of Sciences · 2004 · 1.7K citations · Full text

, , +17

Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

Phoebe D. Lu, Heather P. Harding, David Ron · The Journal of Cell Biology · 2004 · 993 citations · Full text

, , +17

Effects of Intercistronic Length on the Efficiency of Reinitiation by Eucaryotic Ribosomes

Marilyn Kozak · Molecular and Cellular Biology · 1987 · 534 citations · Full text

, , +15

Phosphorylation of eIF2 Directs ATF5 Translational Control in Response to Diverse Stress Conditions

Donghui Zhou, Lakshmi Reddy Palam, Li Jiang et al. · Journal of Biological Chemistry · 2008 · 304 citations · Full text

, , +12

Constraints on reinitiation of translation in mammals

M Kozak · Nucleic Acids Research · 2001 · 300 citations · Full text

, , +16

1–5 of 124

Authors

430

  1. AG
    Alan G. Hinnebusch

    Eunice Kennedy Shriver National Institute of Child Health and Human Development, United States

    9 publications · 949 citations

    9

    h-index

  2. LS
    Leoš Shivaya Valášek

    Czech Academy of Sciences, Institute of Microbiology, Czechia

    8 publications · 483 citations

    8

    h-index

  3. SG
    Stanislava Gunišová

    Czech Academy of Sciences, Institute of Microbiology, Czechia

    7 publications · 348 citations

    7

    h-index

  4. LA
    Lyubov A. Ryabova

    Institut de Biologie Moléculaire des Plantes, France

    7 publications · 629 citations

    7

    h-index

  5. RJ
    Richard J. Jackson

    University of Cambridge, United Kingdom

    5 publications · 377 citations

    5

    h-index

1–5 of 430

Institutions

169

  1. Eunice Kennedy Shriver National Institute of Child Health and Human Development

    Bethesda, United States

    10 h-index

    24 publications

    2.9K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    9 h-index

    38 publications

    3.3K citations

  3. Czech Academy of Sciences, Institute of Microbiology

    Prague, Czechia

    9 h-index

    50 publications

    3.1K citations

  4. Institut de Biologie Moléculaire des Plantes

    Strasbourg, France

    7 h-index

    34 publications

    3.1K citations

  5. University of Cambridge

    Cambridge, United Kingdom

    5 h-index

    19 publications

    1.4K citations

  6. National Institutes of Health

    Bethesda, United States

    5 h-index

    12 publications

    1.1K citations

  7. University of Pittsburgh

    Pittsburgh, United States

    4 h-index

    8 publications

    991 citations

  8. Lomonosov Moscow State University

    Moscow, Russia

    4 h-index

    14 publications

    631 citations

1–8 of 169

Venues

  1. Nucleic Acids Research

    16 publications · 1.2K citations

    14

    h-index

  2. Molecular and Cellular Biology

    MCB · 15 publications · 1.9K citations

    13

    h-index

  3. Journal of Biological Chemistry

    JBC · 10 publications · 843 citations

    10

    h-index

  4. Journal of Virology

    JVI · 9 publications · 571 citations

    9

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 8 publications · 2.1K citations

    8

    h-index

1–5