Concepedia

Initiation Factor Phosphorylation

Initiation Factor Phosphorylation is the covalent modification of translation initiation factors through the addition of phosphate groups, a regulatory mechanism that modulates the activity, assembly, or localization of the translation initiation machinery in eukaryotic cells.

651

Publications

60.4K

Citations

1.9K

Authors

530

Institutions

Publications per year

2017–2026

47

Parents

Publications

651

Feedback Inhibition of the Unfolded Protein Response by <i>GADD34</i>-Mediated Dephosphorylation of eIF2α

Isabel Novoa, Huiqing Zeng, Heather P. Harding et al. · The Journal of Cell Biology · 2001 · 1.4K citations · Full text

, , +17

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

Anne‐Claude Gingras, Steven P. Gygi, Brian Raught et al. · Genes & Development · 1999 · 1.3K citations · Full text

, , +17

mTOR and S6K1 Mediate Assembly of the Translation Preinitiation Complex through Dynamic Protein Interchange and Ordered Phosphorylation Events

Marina K. Holz, Bryan A. Ballif, Steven P. Gygi et al. · Cell · 2005 · 1.2K citations · Full text

, , +17

Phosphorylation of initiation factor 2α by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

Thomas Dever, Lan Feng, Ronald C. Wek et al. · Cell · 1992 · 813 citations

, , +16

Identification and Characterization of Pancreatic Eukaryotic Initiation Factor 2 α-Subunit Kinase, PEK, Involved in Translational Control

Yuguang Shi, Krishna M. Vattem, Ruchira Sood et al. · Molecular and Cellular Biology · 1998 · 769 citations · Full text

, , +17

1–5 of 651

Authors

1.9K

  1. NS
    Nahum Sonenberg

    McGill University, Canada

    29 publications · 6.5K citations

    25

    h-index

  2. CG
    Christopher G. Proud

    University of Dundee, United Kingdom

    31 publications · 2.4K citations

    24

    h-index

  3. JW
    John W.B. Hershey

    University of California, Davis, United States

    25 publications · 3.5K citations

    23

    h-index

  4. TD
    Thomas Dever

    Eunice Kennedy Shriver National Institute of Child Health and Human Development, United States

    22 publications · 2.7K citations

    21

    h-index

  5. RJ
    Randal J. Kaufman

    University of Michigan, United States

    24 publications · 4.1K citations

    21

    h-index

1–5 of 1.9K

Institutions

530

  1. McGill University

    Montreal, Canada

    32 h-index

    106 publications

    26.9K citations

  2. Eunice Kennedy Shriver National Institute of Child Health and Human Development

    Bethesda, United States

    31 h-index

    128 publications

    14.8K citations

  3. National Institutes of Health

    Bethesda, United States

    22 h-index

    74 publications

    8.8K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    22 h-index

    72 publications

    13.6K citations

  5. University of California, Davis

    Davis, United States

    22 h-index

    73 publications

    8.7K citations

  6. Pennsylvania State University

    State College, United States

    20 h-index

    75 publications

    10.7K citations

  7. University of Michigan

    Ann Arbor, United States

    18 h-index

    55 publications

    5.9K citations

  8. University of Washington

    Seattle, United States

    17 h-index

    62 publications

    17.3K citations

1–8 of 530

Venues

  1. Journal of Biological Chemistry

    JBC · 150 publications · 12.6K citations

    65

    h-index

  2. Molecular and Cellular Biology

    MCB · 74 publications · 9.2K citations

    49

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 48 publications · 5.7K citations

    38

    h-index

  4. Journal of Virology

    JVI · 28 publications · 2.3K citations

    23

    h-index

  5. Biochemical Journal

    BJ · 21 publications · 1.3K citations

    18

    h-index

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