Concepedia

Design, synthesis, and biological evaluation of indole-based hydroxamic acid derivatives as histone deacetylase inhibitors

Beier Jiang, Jiaxin Hu, Hao Liu, Zhitao Liu, Mingyao Liu, Hankun Zhang, Xiufeng Pang, Li-Fang Yu

European Journal of Medicinal Chemistry · 2021 · 29 citations · 17 references

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Concepts

References

17

Phase II Multi-Institutional Trial of the Histone Deacetylase Inhibitor Romidepsin As Monotherapy for Patients With Cutaneous T-Cell Lymphoma

Richard Piekarz, Robin Frye, Maria L. Turner et al. · Journal of Clinical Oncology · 2009 · 737 citations · Full text

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Trapoxin, an antitumor cyclic tetrapeptide, is an irreversible inhibitor of mammalian histone deacetylase.

Masako Kijima, Minoru Yoshida, Kenji Sugita et al. · Journal of Biological Chemistry · 1993 · 512 citations · Full text

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MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity <i>in vitro</i> and <i>in vivo</i>

Marielle Fournel, Claire Bonfils, Yu Hou et al. · Molecular Cancer Therapeutics · 2008 · 336 citations · Full text

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JNJ-26481585, a Novel Second-Generation Oral Histone Deacetylase Inhibitor, Shows Broad-Spectrum Preclinical Antitumoral Activity

Janine Arts, Peter King, Ann Marin et al. · Clinical Cancer Research · 2009 · 232 citations

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AXL Is a Potential Target for Therapeutic Intervention in Breast Cancer Progression

Yi-xiang Zhang, Peter G. Knyazev, Yu. V. Cheburkin et al. · Cancer Research · 2008 · 210 citations

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