Kenji Sugita

Trapoxin, an antitumor cyclic tetrapeptide, is an irreversible inhibitor of mammalian histone deacetylase.

Masako Kijima, Minoru Yoshida, Kenji Sugita et al. · Journal of Biological Chemistry · 1993 · 510 citations · Full text

Histone Modifications, Antitumor Cyclic Tetrapeptide, Irreversible Inhibitor +21

Highly Selective and Orally Active Inhibitors of Type IV Collagenase (MMP-9 and MMP-2):  <i>N</i>-Sulfonylamino Acid Derivatives

Yoshinori Tamura, Fumihiko Watanabe, Takuji Nakatani et al. · Journal of Medicinal Chemistry · 1998 · 283 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Chemical Biology +18

Oxamflatin is a novel antitumor compound that inhibits mammalian histone deacetylase

Young Bae Kim, Kun-Hyung Lee, Kenji Sugita et al. · Oncogene · 1999 · 235 citations

Histone Modifications, Cancer Research, Chromatin +11

Isolation and structural elucidation of new cyclotetrapeptides, trapoxins A and B, having detransformation activities as antitumor agents.

Hiroshi Itazaki, K. Nagashima, Kenji Sugita et al. · The Journal of Antibiotics · 1990 · 195 citations · Full text

High-affinity receptor-mediated internalization and degradation of interleukin 2 in human T cells.

Masahiro Fujii, Kazuo Sugamura, Kenji Sano et al. · The Journal of Experimental Medicine · 1986 · 193 citations · Full text

Adaptive Immune System, T-regulatory Cell, Immunology +20