MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity <i>in vitro</i> and <i>in vivo</i>

Marielle Fournel, Claire Bonfils, Yu Hou, +17

Molecular Cancer Therapeutics

Tumor BiologyInhibitory ActivityMedicineHdac IsotypePharmacology +11

RecET direct cloning and Redαβ recombineering of biosynthetic gene clusters, large operons or single genes for heterologous expression

Hailong Wang, Zhen Li, Ruonan Jia, +8

Nature Protocols

BiosynthesisProtein ExpressionLarge OperonsRecet Direct CloningNatural Sciences +10

Association of autoantibody specificity and response to intravenous immunoglobulin G therapy in immune thrombocytopenia: a multicenter cohort study

Jun Peng, Shenglin Ma, J. Liu, +9

Journal of Thrombosis and Haemostasis

ThrombopoiesisThrombosisAutoimmune DiseaseAutoantibody ProductionAutoantibody Specificity +10

CD8+ T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia

Jihua Qiu, Xuena Liu, Xiaoqing Li, +13

Scientific Reports

T-regulatory CellImmunologyPlatelet PhagocytosisPathologyCell Death +18

High‐dose dexamethasone or all‐trans‐retinoic acid restores the balance of macrophages towards M2 in immune thrombocytopenia

Qi Feng, Miao Xu, Yafei Yu, +9

Journal of Thrombosis and Haemostasis

InflammationMacrophages Towards M2CytokineImmunotherapyMedicine +8

Contributions of TRAIL-mediated megakaryocyte apoptosis to impaired megakaryocyte and platelet production in immune thrombocytopenia

Lei Yang, Lin Wang, Chunhong Zhao, +4

Blood

Low-dose decitabine modulates T-cell homeostasis and restores immune tolerance in immune thrombocytopenia

Panpan Han, Yu Hou, Yajing Zhao, +13

Blood

High-dose dexamethasone corrects impaired myeloid-derived suppressor cell function via Ets1 in immune thrombocytopenia

Yu Hou, Qi Feng, Miao Xu, +13

Blood

Low-dose decitabine promotes megakaryocyte maturation and platelet production in healthy controls and immune thrombocytopenia

Hai Zhou, Yu Hou, Xuena Liu, +14

Thrombosis and Haemostasis

Itp PlasmaImmunologyBlood CellPathologyCell Death +21

MiR-223/Ect2/p21 signaling regulates osteosarcoma cell cycle progression and proliferation

Jianli Xu, Qi Yao, Yu Hou, +5

Biomedicine & Pharmacotherapy

Tumor BiologyMedicineCancer Cell BiologyTumor SuppressorMicrorna Detection +4