Concepedia

Co-encapsulation of Cas9 mRNA and guide RNA in polyplex micelles enables genome editing in mouse brain

Saed Abbasi, Satoshi Uchida, Kazuko Toh, Theofilus A. Tockary, Anjaneyulu Dirisala, Kotaro Hayashi, Shigeto Fukushima, Kazunori Kataoka

Journal of Controlled Release · 2021 · 100 citations · 36 references

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References

36

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text

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A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

Linda Madisen, Theresa A. Zwingman, Susan M. Sunkin et al. · Nature Neuroscience · 2009 · 7.4K citations · Full text

, , +10

Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells

Ayal Hendel, Rasmus O. Bak, Joseph T. Clark et al. · Nature Biotechnology · 2015 · 1.1K citations · Full text

, , +12

Identification of preexisting adaptive immunity to Cas9 proteins in humans

Carsten T. Charlesworth, Priyanka S. Deshpande, Daniel P. Dever et al. · Nature Medicine · 2019 · 975 citations · Full text

, , +9

Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy

Chengzu Long, Leonela Amoasii, Alex A. Mireault et al. · Science · 2015 · 935 citations

, , +17