Concepedia

Guide Rna-directed Editing

Guide RNA-Directed Editing is a molecular mechanism in which a small RNA molecule, known as a guide RNA, directs site-specific modifications to a target RNA transcript by forming complementary base pairs and facilitating the enzymatic alteration of specific nucleotides.

311

Publications

37.4K

Citations

1.8K

Authors

538

Institutions

Publications per year

2017–2026

207

Parents

Publications

311

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

Hiroshi Nishimasu, F. Ann Ran, Patrick D. Hsu et al. · Cell · 2014 · 2.4K citations · Full text

, , +15

RNA-programmed genome editing in human cells

Martin Jínek, Alexandra East, Aaron Cheng et al. · eLife · 2013 · 2.2K citations · Full text

, , +15

Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR

Maximilian Haeussler, Kai Schönig, Hélène Eckert et al. · Genome biology · 2016 · 1.9K citations · Full text

, , +14

A CRISPR/Cas9 toolkit for multiplex genome editing in plants

Hui-Li Xing, Dong Li, Zhi-Ping Wang et al. · BMC Plant Biology · 2014 · 1.7K citations · Full text

, , +16

CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites

Yuki Naito, Kimihiro Hino, Hidemasa Bono et al. · Bioinformatics · 2014 · 1.4K citations · Full text

, , +15

1–5 of 311

Authors

1.8K

  1. TS
    Thorsten Stafforst

    University of Tübingen, Germany

    10 publications · 974 citations

    10

    h-index

  2. LS
    Larry Simpson

    University of California, Los Angeles, United States

    9 publications · 729 citations

    9

    h-index

  3. KS
    Kenneth Stuart

    Center for Infectious Disease Research, United States

    9 publications · 585 citations

    9

    h-index

  4. JC
    Jorge Cruz‐Reyes

    Texas A&M University, United States

    6 publications · 214 citations

    6

    h-index

  5. BS
    Barbara Sollner-Webb

    Johns Hopkins University, United States

    5 publications · 220 citations

    5

    h-index

1–5 of 1.8K

Institutions

538

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    18 h-index

    37 publications

    9.5K citations

  2. Chinese Academy of Sciences

    Beijing, China

    12 h-index

    64 publications

    8.4K citations

  3. University of California, Berkeley

    Berkeley, United States

    12 h-index

    56 publications

    17.2K citations

  4. University of Tübingen

    Tübingen, Germany

    11 h-index

    58 publications

    5.9K citations

  5. University of Washington

    Seattle, United States

    10 h-index

    34 publications

    3.1K citations

  6. University of California, Los Angeles

    Los Angeles, United States

    10 h-index

    41 publications

    2.9K citations

  7. Harvard University

    Cambridge, United States

    10 h-index

    35 publications

    11K citations

  8. Massachusetts Institute of Technology

    Cambridge, United States

    9 h-index

    41 publications

    20.3K citations

1–8 of 538

Venues

  1. Nucleic Acids Research

    26 publications · 2.3K citations

    20

    h-index

  2. Scientific Reports

    13 publications · 815 citations

    13

    h-index

  3. Nature Communications

    15 publications · 2K citations

    13

    h-index

  4. PLoS ONE

    9 publications · 1.8K citations

    9

    h-index

  5. Molecular and Cellular Biology

    MCB · 9 publications · 494 citations

    9

    h-index

1–5