RNA-programmed genome editing in human cells

Martin Jínek, Alexandra East, Aaron Cheng, +3

eLife

Off-target EffectHybrid Guide RnasGuide RnaNatural SciencesImmunology +11

A Mouse-Adapted SARS-Coronavirus Causes Disease and Mortality in BALB/c Mice

Anjeanette Roberts, Damon Deming, Christopher D. Paddock, +10

PLoS Pathogens

Lung InflammationViral PathogenesisImmunologyPathologyIntranasal Inoculation +15

Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells

Jeffrey B. Doyon, Bryan Zeitler, Jackie Cheng, +13

Nature Cell Biology

Endocytic PathwayGenome-edited Mammalian CellsIntracellular TraffickingCellular BiochemistrySystems Biology +4

Actin and dynamin2 dynamics and interplay during clathrin-mediated endocytosis

Alexandre Grassart, Aaron Cheng, Sun Hae Hong, +7

The Journal of Cell Biology

The Open Reading Frame 3a Protein of Severe Acute Respiratory Syndrome-Associated Coronavirus Promotes Membrane Rearrangement and Cell Death

Eric C. Freundt, Li Yu, Cynthia S. Goldsmith, +13

Journal of Virology

Early-Arriving Syp1p and Ede1p Function in Endocytic Site Placement and Formation in Budding Yeast

Helen E. M. Stimpson, Christopher P. Toret, Aaron Cheng, +2

Molecular Biology of the Cell

SH3 interactome conserves general function over specific form

Xiaofeng Xin, David Gfeller, Jackie Cheng, +26

Molecular Systems Biology

Genome-edited human stem cells expressing fluorescently labeled endocytic markers allow quantitative analysis of clathrin-mediated endocytosis during differentiation

Daphné Dambournet, Kem A. Sochacki, Aaron Cheng, +4

The Journal of Cell Biology

CytoskeletonStem Cell BiologyCell SpecializationCellular PhysiologyCme Site Dynamics +16

A Tandem Guide RNA-Based Strategy for Efficient CRISPR Gene Editing of Cell Populations with Low Heterogeneity of Edited Alleles

Gérard Joberty, Maria Fälth-Savitski, Marcel Paulmann, +5

The CRISPR Journal

Cellular Target Engagement Approaches to Monitor Epigenetic Reader Domain Interactions

Alexander N. Phillipou, Charles S. Lay, Charlotte E. Carver, +14

SLAS DISCOVERY