A short history of<i>SHELX</i>

George M. Sheldrick

Acta Crystallographica Section A Foundations of Crystallography

Shelx SystemEngineeringMolecular BiologyHistorical LinguisticsHardware Description Language +12

<i>Coot</i>: model-building tools for molecular graphics

Paul Emsley, Kevin Cowtan

Acta Crystallographica Section D Biological Crystallography

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jínek, Krzysztof Chylinski, Ines Fonfara, +3

Science

Crispr RnasAdaptive Bacterial ImmunityCrispr-associated Protein Cas9MedicineGenetics +13

<i>XDS</i>

Wolfgang Kabsch

Acta Crystallographica Section D Biological Crystallography

Geometric ModelingProgram Package XdsImage AnalysisMachine VisionMedical Imaging +12

Multiplex Genome Engineering Using CRISPR/Cas Systems

Le Cong, F. Ann Ran, David Cox, +8

Science

Single Crispr ArrayEngineeringShort RnasGeneticsSynthetic Biology +10

RNA-Guided Human Genome Engineering via Cas9

Prashant Mali, Luhan Yang, Kevin M. Esvelt, +5

Science

EngineeringGeneticsMolecular BiologyCrispr ComponentsMultiple Grnas +14

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

Rodolphe Barrangou, Christophe Fremaux, Hélène Deveau, +5

Science

Phage-resistance PhenotypeGeneticsBacteriophageSpacer-phage Sequence SimilarityAntimicrobial Resistance +10

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

Ophir Shalem, Neville E. Sanjana, Ella Hartenian, +8

Science

EngineeringGeneticsGecko LibraryTumor BiologyHuman Cells +14

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

Lei S. Qi, Matthew H. Larson, Luke A. Gilbert, +4

Cell

Off-target EffectEngineeringRna-guided PlatformGenetic EngineeringMolecular Biology +7

How good are my data and what is the resolution?

Philip R. Evans, Garib N. Murshudov

Acta Crystallographica Section D Biological Crystallography

High ResolutionEngineeringMeasurementNew Scaling ProgramSuper-resolution Imaging +16