Osamu Nureki

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

Silvana Konermann, Mark D. Brigham, Alexandro E. Trevino et al. · Nature · 2014 · 2.9K citations · Full text

Engineered Crispr-cas9 Complex, Transcriptional Regulation, Natural Sciences +8

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

Hiroshi Nishimasu, F. Ann Ran, Patrick D. Hsu et al. · Cell · 2014 · 2.3K citations · Full text

Chromatin, Target Dna, Crystal Structure +12

Crystal Structure of the Complex of Human Epidermal Growth Factor and Receptor Extracellular Domains

Hideo Ogiso, Ryuichiro Ishitani, Osamu Nureki et al. · Cell · 2002 · 1.2K citations · Full text

Crystal Structure, Skin Development, Signal Transduction +8

Engineered CRISPR-Cas9 nuclease with expanded targeting space

Hiroshi Nishimasu, Xi Shi, Soh Ishiguro et al. · Science · 2018 · 1.1K citations · Full text

Integrated molecular analysis of adult T cell leukemia/lymphoma

Keisuke Kataoka, Yasunobu Nagata, Akira Kitanaka et al. · Nature Genetics · 2015 · 825 citations

Lymphoid Neoplasia, Medicine, Mixed-phenotype Acute Leukemia +7