Silvana Konermann

DNA targeting specificity of RNA-guided Cas9 nucleases

Patrick D. Hsu, David A. Scott, Joshua A. Weinstein et al. · Nature Biotechnology · 2013 · 4.8K citations · Full text

Molecular Biology, Gene Editing, Genome Editing +3

Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

F. Ann Ran, Patrick D. Hsu, Chie-Yu Lin et al. · Cell · 2013 · 3.3K citations · Full text

Rna-guided Crispr Cas9, Genetics, Molecular Biology +7

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

Silvana Konermann, Mark D. Brigham, Alexandro E. Trevino et al. · Nature · 2014 · 2.9K citations · Full text

Engineered Crispr-cas9 Complex, Transcriptional Regulation, Natural Sciences +8

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

Hiroshi Nishimasu, F. Ann Ran, Patrick D. Hsu et al. · Cell · 2014 · 2.3K citations · Full text

Chromatin, Target Dna, Crystal Structure +12

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

Omar O. Abudayyeh, Jonathan S. Gootenberg, Silvana Konermann et al. · Science · 2016 · 2.3K citations · Full text