Ayal Hendel

Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells

Ayal Hendel, Rasmus O. Bak, Joseph T. Clark et al. · Nature Biotechnology · 2015 · 1.1K citations · Full text

Natural Sciences, Genetic Engineering, Molecular Biology +9

CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells

Daniel P. Dever, Rasmus O. Bak, Andreas Reinisch et al. · Nature · 2016 · 856 citations · Full text

Crispr/cas9 β-Globin Gene, Stem Cell Research, Gene Editing +4

Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification

Sriram Vaidyanathan, Krist Azizian, A.K.M. Ashiqul Haque et al. · Molecular Therapy — Nucleic Acids · 2018 · 258 citations · Full text

PCNA Ubiquitination Is Important, But Not Essential for Translesion DNA Synthesis in Mammalian Cells

Ayal Hendel, Peter H.L. Krijger, Noam Diamant et al. · PLoS Genetics · 2011 · 136 citations · Full text

Quantifying Genome-Editing Outcomes at Endogenous Loci with SMRT Sequencing

Ayal Hendel, Eric Kildebeck, Eli J. Fine et al. · Cell Reports · 2014 · 133 citations · Full text

Off-target Effect, Functional Genomics, Natural Sciences +15